|
KMID : 1137820160370040134
|
|
의공학회지
2016 Volume.37 No. 4 p.134 ~ p.139
|
|
|
A Effect of Photo Dynamic Therapy for LAZER Wave Mode
|
|
Choi Deog-Su
Lim Hyun-Soo
Lee Byung-Koo
Necla Kenar
|
|
|
Abstract
|
|
|
|
US Food and Drug Administration (FDA) approved as a innovative cure for cancer, 1996. The effect is death of cancer cells through necrosis, apoptosis. Mainly the Continuous Wave mode (CW) use for PDT Laser. It sting, the question including itch, and etc. Reportedly, the increase of temperature with the perforated edema, ulcer, necrosis. The Thermal relaxation time and Oxygen recovery time is necessary. To give a normal oxygen recovery time of the cell, used Pulse mode. Progress, it was Burst Pulse mode when easing the thermal wake, the simplicity was secured, the PDT effect is good. Excepted in control group CW, Pulse, Burst pulse mode were incubated with various concentrations of 5-aminolevulinic acid hydrochloride (ALA-5). The tumor size reduction CW mode (44%), Pulse mode (48%), Burst pulse mode (53%) at 4 week after PDT with 0.3, 0.3, 0.3 mg/ml of ALA-5. After 4 hours, investigation of 100, 100, 100 J/cm2 laser irradiation. The pulse mode was superior in expirimental data analysis. And it was the Burst pulse mode edge head of a family effect.
|
|
|
KEYWORD
|
|
|
Photo Dynamic Therapy (PDT), Continuous Wave mode (CW), Pulse mode, Burst pulse mode, 5-aminolevulinic acid hydrochloride (ALA-5)
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|